Vasoproliferative tumour

This is a rare, benign tumour consisting of tiny, abnormal blood vessels. It can occur in isolation or may be association with conditions such as retinitis pigmentosa, inflammation and ocular injury. 


Vasoproliferative tumours tend to leak fluid and fatty exudates into the retina, which can become detached. 



Vasoproliferative tumour with adjacent exudation and retinal detachment


Loss of vision can occur if the macula is affected by exudates or a cellophane membrane.


Some vasoproliferative tumours may remain dormant and asymptomatic for many years.



Asymptomatic vasoproliferative tumour near inferior ora



A variety of methods may be used. The following are listed in order of increasing invasiveness/morbidity:

  • Photodynamic therapy
  • Intraocular anti-VEGF agents
  • Cryotherapy
  • Plaque radiotherapy


Many patients require surgical treatment of vitreoretinal traction and cellophane maculopathy.