These are very rare tumours arising from particular membranes inside the eye (i.e., retinal pigment epithelium and ciliary epithelium). They can be benign or malignant. If malignant, they can invade local tissues within and around the eye but do not usually spread to other parts of the body.



RPE adenocarcinoma in the supero-temporal periphery of the left eye. Note the deep pigmentation, discrete margins and feeder vessels.



Iridocyclectomy, for small, ciliary body tumours

Brachytherapy, proton beam radiotherapy and stereotactic radiotherapy are of uncertain efficacy.